Tosyl compounds
Medchemexpress LLC Biotin sulfone | 40720-05-6 | 99.8% | 276.31 | 25 MG
Biotin sulfone is a structural analog and metabolite of Biotin. It competitively inhibits Biotin in Lactobacillus arabinosus 17-5. The inhibitory potency is regulated by medium additives, with the inhibition index increasing with aspartic acid, Tween 80, and a combination of lysine, threonine, and uracil. Biotin sulfone binds tightly to streptavidin with performance comparable to that of Biotin.
- Structural analog and metabolite of Biotin
- Competitively inhibits Biotin in Lactobacillus arabinosus 17-5
- Binds tightly to streptavidin
- Appearance: Solid, white to off-white
- Can be stored for extended periods in powder form
- Detailed solubility and dissolution protocols provided for in vitro and in vivo experiments
![Medchemexpress LLC Pyridine, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-5-yl]- | 152121-46-5 | 99.25% | 393.43 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436772-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Pyridine, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-5-yl]- | 152121-46-5 | 99.25% | 393.43 | 50 MG
SB 203580 sulfone is an analog of p38 MAP kinase inhibitor SB 203580. It is known for its ability to inhibit IL-1 production and bind competitively with CSAID binding proteins (CSBP). This compound is used in the research of inflammatory diseases and stress response signaling.
- Analog of p38 MAP kinase inhibitor SB 203580
- Inhibits IL-1 production (IC50 of 0.2 μM in monocytes)
- Binds competitively with CSBP
- Inhibits stress response signaling (IC50 of 0.03 μΜ)
- Inhibits 5-LO (IC50 value of 24 μM)
- Suitable for research of inflammatory diseases
Medchemexpress LLC N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride | 4272-74-6 | 99.0% | 369.31 | 1 ML
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK) is a trypsin-like protease inhibitor that sensitizes HeLa cells to Fas-mediated cell death. It exhibits an inhibitory effect on IFN-γ activities and enhances the decrease in cell survival when combined with anti-Fas. This product is for research use only.
- Acts as a trypsin-like protease inhibitor
- Sensitizes HeLa cells to Fas-mediated cell death
- Inhibits IFN-γ activities
- Enhances cell death in combination with anti-Fas
- Suitable for research applications
Medchemexpress LLC Biotin sulfone | 40720-05-6 | 99.8% | 276.31 | 10 MG
Biotin sulfone is a structural analog and metabolite of Biotin. It competitively inhibits Biotin in *Lactobacillus arabinosus* 17-5 and binds tightly to streptavidin.
- Competitively inhibits biotin utilization by *Lactobacillus arabinosus*
- Binds tightly to streptavidin
- Soluble in DMSO at 250 mg/mL
- Available as a solid